Virus shows promise for imaging and treating pancreatic cancer
Researchers are investigating a potential treatment and noninvasive imaging modality for pancreatic cancer that shows promise, according to researchers at Memorial Sloan-Kettering Cancer Center in New...
View ArticleViruses kill pancreatic tumors in preclinical model
(Medical Xpress) -- An intra-tumor injection of a virus prevented further growth of some pancreatic tumors and eradicated others in mouse models of pancreatic ductal adenocarcinoma. However, some...
View ArticleBlood vessel 'inflator' could be 'game-changer' for pancreatic cancer treatment
(Medical Xpress) -- Cancer Research UK scientists have shown that an enzyme can re-expand the insides of blood vessels allowing more drugs and large antibody molecules to reach pancreatic tumors,...
View ArticleElectrical pulse treatment gives pancreatic cancer patients new hope
Results of a study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif., signal a light at the end of the tunnel for individuals with...
View ArticleChemo may get boost from cholesterol-related drug
Johns Hopkins investigators are testing a way to use drugs that target a cholesterol pathway to enhance the cancer-killing potential of standard chemotherapy drugs. Their tests, in mouse models of...
View ArticleAdvanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to...
View ArticleStudies show that pancreatic cancer can run but not always hide from the...
A pair of recent studies describes how pancreatic cancer cells produce a protein that attracts the body's immune cells and tricks them into helping cancer cells grow. The research, published by Cell...
View ArticleLeukemia inhibitory factor may be a promising target against pancreatic cancer
Pancreatic cancer is one of the deadliest forms of cancer, defying most treatments. Its ability to evade therapy may be attributable to the presence of cancer stem cells, a subset of cancer cells...
View ArticleLoyola surgeons remove extremely rare tumor from 9-year-old girl
(Medical Xpress) -- Loyola University Medical Center surgeons have successfully removed an extremely rare pancreatic tumor from a patient who was only 9 years old.
View ArticleCancer-causing gene alone doesn't trigger pancreatic cancer, study finds
More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say....
View ArticleGenome analysis of pancreas tumors reveals new pathway
The latest genomic analysis of pancreatic tumors identified two new pathways involved in the disease, information that could be capitalized on to develop new and earlier diagnostic tests for the disease
View ArticleScientists find new molecule to target in pancreatic cancer treatment
Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases....
View ArticleStorming the gates: Study probes how pancreatic cancers metastasize
Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts...
View ArticleScientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with...
View ArticleBlocking 'scaffold' protein inhibits cancer growth, study finds
(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of...
View ArticleBreakthrough in how pancreatic cancer cells ingest nutrients points to new...
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new...
View ArticleScientists identify possible KRAS downstream target for pancreatic cancer...
While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by...
View ArticleRadiopeptide therapy improves survival outcomes for neuroendocrine cancer...
Peptide-receptor radionuclide therapy (PRRT) has been a subject of growing research on neuroendocrine tumors, which take up residence in a variety of organs replete with nerve cells that respond to...
View ArticleAntibody-drug conjugate may provide new treatment option for pancreatic...
Patients with pancreatic cancer may benefit from an investigational member of an emerging class of anticancer drugs called antibody-drug conjugates, according to preclinical results presented here at...
View ArticleStudy confirms fibroblast growth factor receptors as targets for pancreatic...
Proteins called fibroblast growth factor receptors (FGFRs) have been implicated in the development of pancreatic cancer, which remains difficult to treat. Researchers at Roswell Park Cancer Institute...
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